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Immunological evidence for an inactive precursor of collagen proline hydroxylase in cultured fibroblasts.
- J. Mcgee, U. Langness, S. Udenfriend
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 1 July 1971
A specific antibody to rat collagen proline hydroxylase has been used to measure the amount of "enzyme" protein in cultured mouse fibroblasts (L-929 cells) during normal growth, and under other… Expand
Collagen biosynthesis in nonfibroblastic cell lines.
Prolyl hydroxylase and other enzymes of collagen synthesis have been found in cloned cells, including epithelium, melanoma, liver, HeLa, pituitary, kidney, and neuroblastoma. The significance of… Expand
[Biochemical studies on osteogenesis imperfecta].
[Proliferation of L 929 mouse fibroblasts and their glycosaminoglycan synthesis in monolayer cultures after addition of penicillamine, azathioprine, gold thiopolypeptide, oxyphenbutazone and…
L 929 mouse fibroblasts were cultured as monolayers. Proliferation and glycosaminoglycan content in cells and medium were measured, the different glycosaminoglycans fractionated. It was shown that… Expand
Light and electron microscopic and element analysis of pseudoxanthoma elasticum (Darier-Grönblad-Strandberg syndrome).
- S. Blümcke, U. Langness, B. Liesegang, M. Fooke-Achterrath, H. Thiel
- Chemistry, Medicine
- Beitrage zur Pathologie
- 1 July 1974
Summary Skin biopsies from 6 patients aged 9–57 years with typical Pseudoxanthoma elasticum (PXE) were investigated. “Semithin” sections of the corium revealed bizarre deformations and central… Expand
Differentiation of inflammation and ossification in spondylarthritis ankylopoietica.
- U. Langness, D. Banavsky, J. Alexopulos, W. Kriegel, R. Burger
- Acta rheumatologica Scandinavica
SummaryIn 50 patients with classic spondylarthritis ankylopoietica, the “collagen-like” protein (CLP), the immune globulins, the SR and the alpha2-globulin fraction, besides clinical and x-ray… Expand
[Clinical picture and genetics of osteogenesis imperfecta].
Collagen metabolites in plasma and urine in osteogenesis imperfecta.
Abstract Collagen metabolism was studied in 16 patients with osteogenesis imperfecta by measuring hyproprotein in plasma as well as free and peptide-bound hydroxyproline in plasma and urine. Results… Expand