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Pax‐3, a novel murine DNA binding protein expressed during early neurogenesis.
- M. Goulding, G. Chalepakis, U. Deutsch, J. R. Erselius, P. Gruss
- Biology, Medicine
- The EMBO journal
- 1 May 1991
We describe the isolation and characterization of Pax‐3, a novel murine paired box gene expressed exclusively during embryogenesis. Pax‐3 encodes a 479 amino acid protein with an Mr of 56 kd… Expand
Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system.
The murine genome contains multiple genes with protein domains homologous to the Drosophila paired box, present in certain segmentation genes. At least one of these murine paired box (Pax) genes is… Expand
Structural and Functional Diversity of Connexin Genes in the Mouse and Human Genome
Abstract Gap junctions are clustered channels between contacting cells through which direct intercellular communication via diffusion of ions and metabolites can occur. Two hemichannels, each built… Expand
Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development
The mouse genome contains at least three copies of sequences homologous to the "paired box", a conserved domain in several Drosophila segmentation genes of the pair-rule and segment polarity classes.… Expand
Spatially and temporally restricted expression of Pax2 during murine neurogenesis.
The expression of the murine paired-box-containing gene, Pax2, is examined in the developing central nervous system by in situ hybridization. Pax2 expression is detected along the boundaries of… Expand
The molecular basis of the undulated/Pax-1 mutation
- G. Chalepakis, R. Fritsch, H. Fickenscher, U. Deutsch, P. Gruss
- Biology, Medicine
- 6 September 1991
The murine paired box gene Pax-1 has been associated with the mouse developmental mutant undulated (un), which exhibits malformations in the vertebral column. In un mice, a point mutation leading to… Expand
Pax: a murine multigene family of paired box-containing genes.
A murine multigene family has been identified that shares a conserved sequence motif, the paired box, with developmental control and tissue-specific genes of Drosophila. To date five murine paired… Expand
undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1
undulated (un) homozygous mice exhibit vertebral malformations along the entire rostro-caudal axis. Pax 1, a murine paired box-containing gene, is expressed in ventral sclerotome cells and later in… Expand
Fritz: a secreted frizzled-related protein that inhibits Wnt activity
Signaling molecules of the Wnt gene family are involved in the regulation of dorso-ventral, segmental and tissue polarity in Xenopus and Drosophila embryos. Members of the frizzled gene family, such… Expand
VE-PTP controls blood vessel development by balancing Tie-2 activity
1. 1. Winderlich, 2. et al . 2009. J. Cell Biol. doi:10.1083/jcb.200811159 [OpenUrl][Abstract/FREE Full Text] :… Expand