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Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: A combinatorial study with azithromycin and gentamicin
Microbial biofilm are communities of surface-adhered cells enclosed in a matrix of extracellular polymeric substances. Extensive use of antibiotics to treat biofilm associated infections has led toExpand
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Inhibiting epidermal growth factor receptor signalling potentiates mesenchymal–epithelial transition of breast cancer stem cells and their responsiveness to anticancer drugs
The recurrence of breast cancer in patients is a persistent challenge to the medical fraternity. Breast tumor contains a small population of cells with high tumor initiating and metastatic potential,Expand
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New flavonoids from the fruits of Cornus mas, Cornaceae
One new β-hydroxychalcone, 4-acetoxy-5,2′,4′,6′,β-pentahydroxy-3-methoxychalcone (1), one new flavanone, 7,3′-dihydroxy-5,4′-dimethoxyflavanone (2) and seven known compounds, 2R,Expand
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Parkia javanica Extract Induces Apoptosis in S-180 Cells via the Intrinsic Pathway of Apoptosis
ABSTRACT Parkia javanica is a leguminous tree, various parts of which are used as food and folklore medicine by the ethnic groups of northeastern India. The present study investigates the in vitroExpand
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Inguinal dermoid cyst masquerading as irriducible inguinal hernia: A case report
Introduction: Dermoid cysts are common developmental anomalies occurring along embryonic fusion lines. Occurrence of this in inguinal region is rare and imposes diagnostic challenge as it masqueradesExpand
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Antileishmanial and immunomodulatory activities of lupeol, a triterpene compound isolated from Sterculia villosa.
Visceral leishmaniasis (VL) is one of the most severe forms of leishmaniasis, caused by the protozoan parasite Leishmania donovani. Nowadays there is a growing interest in the therapeutic use ofExpand
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New flavonol methyl ether from the leaves of Vitex peduncularis exhibits potential inhibitory activity against Leishmania donovani through activation of iNOS expression.
One new flavonol methyl ether (1), along with four known compounds from the leaves of methanol extract of Vitex peduncularis Wall and three known compounds from the leaves of methanol extract ofExpand
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Antibiofilm activity of Parkia javanica against Pseudomonas aeruginosa: a study with fruit extract
Parkia javanica is a well-known ethno-botanical plant of the north-east region of India. Ethnic communities of the region use several parts, including fruits, of this plant for the treatment ofExpand
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ANTIBACTERIAL, ANTI-ALPHA GLUCOSIDASE AND ANTIOXIDANT PROPERTIES OF DILLENIA PENTAGYNA ROXB. (DILLENIACEAE)
Objective: The persent investigation is carried out to assess in vitro antimicrobial, antioxidant and anti-alphaglucosidase activity of the crude and fraction extracts of both leaf and fruits of theExpand
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Vitexin alters Staphylococcus aureus surface hydrophobicity to interfere with biofilm formation
Bacterial surface hydrophobicity is one of the determinant biophysical parameters of bacterial aggregation for being networked to form biofilm. Phytoconstituents like vitexin have long been in useExpand
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