• Publications
  • Influence
Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas.
Comparative genomic hybridization was performed on 30 primary head and neck squamous cell carcinomas. Fractional or entire DNA loss of chromosome 3p was a basic finding that occurred in 29 casesExpand
  • 168
  • 10
  • PDF
Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers.
Glutathione S-transferase GSTM1, GSTM3 and GSTT1 and cytochrome P450 CYP2D6, CYP1A1 and CYP2E1 loci are susceptibility candidates for cancers of the upper aerodigestive tract because putativelyExpand
  • 162
  • 10
Genetic imbalances with impact on survival in head and neck cancer patients.
Chromosomal imbalances in 113 primary head and neck squamous cell carcinomas (HNSCCs) determined by comparative genomic hybridization were correlated with patients survival using custom-made computerExpand
  • 138
  • 10
Cyclin D1 polymorphism and expression in patients with squamous cell carcinoma of the head and neck.
We have previously reported that the cyclin D1 (CCND1) GG870 genotype was associated with poorly differentiated tumors and reduced disease-free interval in patients with squamous cell carcinoma ofExpand
  • 91
  • 9
Malignant peripheral nerve sheath tumors of the head and neck: Management of 10 cases and literature review
This study analyzes the management and outcomes of a series of 10 malignant peripheral nerve sheath tumors (MPNST) of the head and neck.
  • 82
  • 9
  • PDF
The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas.
We have examined the hypothesis that the polymorphic, glutathione S-transferase GSTP1 gene is a susceptibility candidate for squamous cell cancer of the oral/pharynx and larynx. We describe GSTP1Expand
  • 122
  • 8
Cervical paragangliomas-tumor control and long-term functional results after surgery.
OBJECTIVE To report long-term functional results of the surgical treatment of cervical paragangliomas. PATIENTS AND METHODS A retrospective review of 22 patients with 34 head and neckExpand
  • 57
  • 7
Genomic alterations associated with malignancy in head and neck cancer
Comparative genomic hybridization (CGH) was performed on 50 primary head and neck squamous cell carcinomas (HNSCC) to discover molecular genetic alterations underlying the progression of these tumors.
  • 131
  • 5
Is the p53 inactivation frequency in squamous cell carcinomas of the head and neck underestimated? Analysis of p53 exons 2-11 and human papillomavirus 16/18 E6 transcripts in 123 unselected tumor
Mutations and interaction with high-risk human papillomavirus (HPV) E6 oncoprotein are well-established mechanisms of p53 inactivation. In a series of 123 unselected squamous cell carcinomas of theExpand
  • 154
  • 4
Chromosomal alterations during metastasis formation of head and neck squamous cell carcinoma
Comparative genomic hybridization (CGH) was used to detect chromosomal changes during metastasis formation of head and neck squamous cell carcinomas (HNSCCs). In total, 92 tumors of 54 patients wereExpand
  • 82
  • 4