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Review on uremic toxins: classification, concentration, and interindividual variability.
BACKGROUND The choice of the correct concentration of potential uremic toxins for in vitro, ex vivo, and in vivo experiments remains a major area of concern; errors at this level might result inExpand
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A bench to bedside view of uremic toxins.
Reviewing the current picture of uremic toxicity reveals its complexity. Focusing on cardiovascular damage as a model of uremic effects resulting in substantial morbidity and mortality, mostExpand
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Turbulent flow technique for the estimation of oxygen diffusive permeability of membranes for the oxygenation of blood and other cell suspensions
When transport-efficient membrane modules (such as those where the liquid flows outside hollow fibre membranes) or membranes with prolonged resistance to wetting are used for the oxygenation of bloodExpand
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Dialyzer membranes: effect of surface area and chemical modification of cellulose on complement and platelet activation.
Using an ex vivo model, the effects of membrane composition and surface area on both the complement system (as reflected by plasma C3a levels) and platelets [as indicated by plasma concentrations ofExpand
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A clinical study on different cellulosic dialysis membranes.
A controlled clinical study was performed over a period of 8 weeks in two dialysis centres (Rostock, GDR, and Munich, FRG). The aim was to compare a dialysis membrane made of modified celluloseExpand
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Cellulosic versus synthetic membranes: a reasonable comparison?
Of the two main classes of dialysis membranes, cellulosic and synthetic, the former represents the standard membrane used in dialysis therapy. The disputed properties of cellulosic membranes relatedExpand
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Ex vivo biocompatibility evaluation of a new modified cellulose membrane.
To evaluate membrane biocompatibility, an open loop ex vivo model was designed simulating the hemodialysis procedure. Blood was withdrawn continuously from healthy nonuremic donors, heparinized, andExpand
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Ethylene oxide in dialyzer rinsing fluid: effect of rinsing technique, dialyzer storage time, and potting compound.
Ethylene oxide (ETO) is recognized as one of the main causes of dialyzer-associated hypersensitivity reactions. We studied the amount of ETO in the rinsing fluid of ETO-sterilized hollow-fiberExpand
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Dialysate contamination and back filtration may limit the use of high-flux dialysis membranes.
Endotoxins, or fragments thereof, can reach the blood stream of dialysis patients, transported by diffusion and connection across the intact high-flux membrane. This transfer depends upon theExpand
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