U W Wijesiri

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Analyses were performed on lipid data from the NHLBI Veteran Twin Study. The analyses focused on longitudinal multivariate models, describing how the genetic effects on lipids vary over time. Our pedigree-based model selection approach allows simultaneous estimation of both covariance structure parameters and regression parameters. The analyses reveal(More)
We present numerical results concerning the accuracy of approximate maximum-likelihood estimators of variance components for several models of univariate human twin data. The approximations are obtained via a spectral decomposition of the twin model covariance matrix. The results apply to likelihood functions for univariate twin data based on either the(More)
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