U Schollmeier

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The new sulfonylurea glimepiride (Hoe 490, CAS 93479-97-1) was tested in subchronic and chronic toxicity studies in dogs. Up to and including a dose of 16 mg/kg b.w. neither toxic effects nor pathological changes were observed in the treated animals. Also at a dose of 320 mg/kg b.w. which was applied over a period of 6 months no undesired effects were(More)
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