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Our experience of the fi rst wave of paediatric H1N1 swine-origin infl uenza admissions in Birmingham, UK, shows that presentations can be atypical, severity is often associated with underlying disease, and rates of secondary bacterial infection are low. We reviewed the 78 available case notes of 89 children positive for H1N1 infl uenza by PCR admitted to(More)
Group B streptococcus (GBS) is a leading cause of invasive disease in infants. Accurate and rapid diagnosis is crucial to reduce morbidity and mortality. Real-time polymerase chain reaction (PCR) targeting the dltR gene was utilised for the direct detection of GBS DNA in blood and cerebrospinal fluid (CSF) from infants at an Irish maternity hospital. A(More)
Perinatal transmission is the most common mode of hepatitis B virus (HBV) transmission and is a leading cause of chronic infection worldwide. Maternal treatment with lamivudine (LAM) can result in a rapid and significant reduction in HBV viral load (VL) and, thus, mitigate the risk of mother-to-child transmission (MTCT). The aim of this study was to(More)
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