U Mädler

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Glutamate decarboxylase immunoreactivity has been located in the thoracic ganglia of the locust, Locusta migratoria, using an antiserum raised from rat brain. At the light microscopic level clusters of nerve cell somata as well as nerve fibres were positively labelled by the antiserum. Electron microscopy showed that glutamic acid decarboxylase was(More)
A polyclonal, monospecific antiserum raised against a nicotinic acetylcholine receptor protein affinity-purified from insect nervous tissue, was employed to demonstrate the localization of antigenic sites in the neuropile of the terminal (sixth) abdominal ganglion of the cockroach Periplaneta americana. In agreement with previously published(More)
Monoclonal antibodies have been isolated that specifically block the high affinity, Na(+)-dependent transport of choline in insect synaptosomes and synaptosomal ghosts. Antibodies were derived after immunization of mice with synaptosomal membranes from locust. Antibody VIB6F5, an IgG isotype, significantly inhibited the high affinity translocation of(More)
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