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PURPOSE Increased T2 signal intensity (SI) can be regularly observed in myocardial infarction. However, there are controversial reports about the relationship of elevated T2 SI to myocardial viability and some authors propose that high T2 SI serves as a sign of irreversible myocardial injury. This study investigates increased T2 SI compared to myocardial(More)
RATIONALE AND OBJECTIVES The aim of the study was to determine optimal thresholds for semiquantitative perfusion parameters and to evaluate the influence of different segmentation models in detecting malperfused regions. MATERIAL AND METHODS In 6 healthy subjects and 13 patients with coronary artery disease, contrast-enhanced first-pass perfusion imaging(More)
OBJECTIVE Cardiac magnetic resonance imaging (MRI) at 3.0 T has recently become available and potentially provides a significant improvement of tissue contrast in T1-weighted imaging techniques relying on Gd-based contrast enhancement. Imaging at high-field strength may be especially advantageous for methods relying on strong T1-weighting and imaging after(More)
In order to find a non-invasive method for determining the hemispheric dominance for language, we studied cortical activation patterns during language processing by means of electrophysiological techniques: DC-potentials were recorded from frontal, central, temporal and parietal electrode positions in 28 right-handed normal subjects and in 16 patients with(More)
PURPOSE To prospectively assess myocardial perfusion before and after successful intervention in patients suspected of having single-vessel coronary artery disease by using a steady-state free precession (SSFP) perfusion magnetic resonance (MR) imaging sequence. MATERIALS AND METHODS Local ethics committee approval and informed consent were obtained.(More)
OBJECTIVES We sought to examine whether the disturbed fibrinolytic system in patients with an acute coronary syndrome is associated with a reduced endothelial fibrinolytic capacity. BACKGROUND Intracoronary thrombus formation is a frequent finding in acute coronary syndromes. Systemic alterations of coagulation and fibrinolysis are known to occur, but(More)
AIM 18F-fluorodeoxyglucose (18F-FDG)-positron emission tomography (PET) provides information about myocardial glucose metabolism to diagnose myocardial viability. Additional information about the functional status is necessary. Comparison of tomographic metabolic PET with data from other imaging techniques is always hampered by some transfer uncertainty and(More)
PURPOSE To compare signal-to-noise ratio (SNR), contrast-to-noise (CNR) ratio, and diagnostic accuracy of a newly developed saturation recovery (SR)-TrueFISP-two-dimensional (2D) sequence with an SR-TurboFLASH-2D sequence. MATERIALS AND METHODS In seven healthy subjects and nine patients with coronary artery disease (CAD), contrast-enhanced perfusion(More)
OBJECTIVES The purpose of the study was to evaluate the cardiopulmonary exercise capacity and ventilatory function in adults with atrial septal defect (ASD) preoperatively and 4 months and 10 years postoperatively. BACKGROUND Only few data are available on cardiopulmonary exercise tolerance after ASD closure, but detailed knowledge might be helpful for(More)
RATIONALE AND OBJECTIVES In functional cardiac magnetic resonance imaging, reduction of measuring time is very important for many patients who are not able to rest motionless for long-lasting examinations. In this study, the image quality of sequences with k-space segmented data recording was compared with conventional gradient-echo sequences for cine(More)