U. Hache

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Lactate and pyruvate were studied comparatively in perilymph (PL), blood, and cerebrospinal fluid (CSF) of anesthetized guinea pigs. Arterial blood pressure, heart and respiration rate (Fig. 1), and arterial blood-gas state (Table 2) were simultaneously checked in a group of the animals. The metabolites were determined enzymatically by using the(More)
Glucose, pyruvate, and lactate of perilymph (PL), blood, and cerebrospinal fluid (CSF) of unexposed and sound-exposed guinea pigs under ethyl urethane anesthesia were examined with due consideration of the principal sources of error. The animals had fasted for 15--20 h before the experiment to stabilize the blood glucose level. The metabolites were(More)
Lactate and pyruvate of perilymph (PL) were studied 30, 60, and 120 min postmortem. During this period the mean lactate concentration of scala tympani and scala vestibuli increased from 4.8 mmol/l found intravitally to 17.8 and 15.1 mmol/l, respectively, whereas pyruvate decreased from an average of 0.33 to 0.10 mmol/l (fig. 1). These inverse changes of(More)
The paper deals with comparative studies of lactate concentration in the perilymph (PL) of scala tympani and of scala vestibuli, arterial and venous blood, serum and cerebrospinal fluid (CSF) of normal and sound exposed guinea pigs, special consideration having been given to possible sources of error in the methods employed. Lactate was determined(More)
The paper deals with: 1. the protein concentration in the perilymph (PL), the serum and the cerebrospinal fluid (CSF), 2. the protein pattern in the PL and 3. histological findings in the middle and inner ear in unilaterally ear-infected guinea pigs. The studies were performed 6 h to 21 days post infectionem (Fig. 1). The pathological changes in the middle(More)
The paper deals with: 1. the protein concentration in the perilymph (PL), the serum and the cerebrospinal fluid (CSF), 2. the protein pattern in the PL and 3. histological findings in the middle and inner ear in unilaterally ear-infected guinea pigs. The studies were performed 6 h to 21 days post infectionem (Fig. 1). The pathological changes in the middle(More)
Glucose, pyruvate, and lactate of perilymph (PL), blood, and cerebrospinal fluid (CSF) of unexposed and sound-exposed guinea pigs under ethyl urethane anesthesia were examined with due consideration of the principal sources of error. The animals had fasted for 15–20 h before the experiment to stabilize the blood glucose level. The metabolites were(More)
Perilymph and serum of guinea pigs were investigated using immunoelectrophoresis and polyacrylamide gel electrophoresis. The molecular weights of the perilymph proteins were estimated by electrophoresis in a linear polyacrylamide gel gradient (3-20%). The immunoelectropherograms and the polyacrylamide gel electropherograms of equivalent amounts of perilymph(More)
The protein concentration in the perilymph of noise-exposed guinea pigs was investigated using a micromethod described previously. The animals were exposed to wide band noise at 140 dB for one hour unilaterally in a closed acoustic system. Perilymph was obtained after exposure at different intervals: immediately, 6 or 24 hours later. From animals exposed to(More)