Tzu-Yu Liu

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We introduce an approach to sparsity penalized multi-class classifier design that accounts for multi-block structure of the data. The unified multi-class classifier is parameterized by a set of weights defined over the classes and over the blocks. The proposed sparse multi-block multi-class classifier imposes structured sparsity on the weights so that the(More)
Modern developments in light microscopy have allowed the observation of cell deformation with remarkable spatiotemporal resolution and reproducibility. Analyzing such phenomena is of particular interest for the signal processing and computer vision communities due to the numerous computational challenges involved, from image acquisition all the way to shape(More)
Early, presymptomatic intervention with oseltamivir (corresponding to the onset of a published host-based genomic signature of influenza infection) resulted in decreased overall influenza symptoms (aggregate symptom scores of 23.5 vs 46.3), more rapid resolution of clinical disease (20 hours earlier), reduced viral shedding (total median tissue culture(More)
Consider the problem of designing a panel of complex biomarkers to predict a patient’s health or disease state when one can pair his or her current test sample, called a target sample, with the patient’s previously acquired healthy sample, called a reference sample. As contrasted to a population averaged reference this reference sample is individualized.(More)
MOTIVATION Ribosome profiling is a useful technique for studying translational dynamics and quantifying protein synthesis. Applications of this technique have shown that ribosomes are not uniformly distributed along mRNA transcripts. Understanding how each transcript-specific distribution arises is important for unraveling the translation mechanism. (More)
Neuropeptide FF (NPFF) is a morphine-modulating peptide that regulates the analgesic effect of opioids, and also controls food consumption and cardiovascular function through its interaction with two cognate receptors, NPFFR1 and NPFFR2. In the present study, we explore a novel modulatory role for NPFF-NPFFR2 in stress-related depressive behaviors. In a(More)
We designed activities for learning English as a foreign language in a mobile learning environment with familiar authentic support for this study. Students learned at school and then applied their newly gained knowledge to solve daily life problems by first using a tablet to take pictures of objects they wished to learn about, then describing them and(More)