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From midbody protein-protein interaction network construction to novel regulators in cytokinesis.
Midbody, a transient organelle-like structure, is known as central for abscission and is indispensable for termination of cytokinesis. Here, we used the midbody proteome inventories to construct theExpand
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POINeT: protein interactome with sub-network analysis and hub prioritization
We have constructed an integrated web service, POINeT, to simplify the process of PPI searching, analysis, and visualization by combining PPI and tissue-specific expression data from multiple resources. Expand
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Structural and Functional Analysis of the cis-Acting Elements Required for Plus-Strand RNA Synthesis of Bamboo Mosaic Virus
ABSTRACT Bamboo mosaic virus (BaMV) has a single-stranded positive-sense RNA genome. The secondary structure of the 3′-terminal sequence of the minus-strand RNA has been predicted by MFOLD andExpand
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Protein Phosphorylation Profiling Using an In Situ Proximity Ligation Assay: Phosphorylation of AURKA-Elicited EGFR-Thr654 and EGFR-Ser1046 in Lung Cancer Cells
The epidermal growth factor receptor (EGFR), which is up-regulated in lung cancer, involves the activation of mitogenic signals and triggers multiple signaling cascades. To dissect these EGFRExpand
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Baseline hypertension: new insight into the potential predictors of survival in patients with hepatocellular carcinoma.
with hepatocellular carcinoma Yu-Feng Hu , Tzu-Chi Chen , Gar-Yang Chau , Tsung-Lin Yang , Chia-Jen Liu , Ming-Huang Chen , Peter Mu-hsin Chang , Tzeng-Ji Chen , Michael Hsiao , Chi-Ying F. Huang ⁎,Expand
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Analysis of Protein-Protein Interactions in Cross-talk Pathways Reveals CRKL Protein as a Novel Prognostic Marker in Hepatocellular Carcinoma*
Deciphering the network of signaling pathways in cancer via protein-protein interactions (PPIs) at the cellular level is a promising approach but remains incomplete. We used an in situ proximityExpand
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Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.
Signal transduction pathways in the cell require protein-protein interactions (PPIs) to respond to environmental cues. Diverse experimental techniques for detecting PPIs have been developed. However,Expand
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Differential network biology reveals a positive correlation between a novel protein-protein interaction and cancer cells migration
This paper introduces a differential network biology for discovering tumor migration in hepatocellular carcinoma. Expand
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AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis
Drug resistance is the main obstacle in the improvement of chemotherapeutic efficacy in glioblastoma. Previously, we showed that dehydroepiandrosterone (DHEA), one kind of androgen/neurosteroid,Expand
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High Expression of CHRNA1 is Associated with Reduced Survival in Early Stage Lung Adenocarcinoma after Complete Resection
BackgroundNon-small cell lung cancer (NSCLC) is the leading cause of cancer deaths around the world, and a high recurrence rate after complete resection is an important issue reducing the cure rateExpand
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