Tyra Ellen Dunn-Thomas

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Previous studies have transplanted a variety of neural stem cells (NSCs) to the eye in hopes of developing a therapy to replace retinal neurons lost to disease. Successful integration, survival, and differentiation of the cell types has been variably successful. At the moment, little is known about the fundamental biological differences between stem cell or(More)
vii CHAPTER 1. GENERAL INTRODUCTION INTRODCUTION 1 RETINAL DEVELOPMENT 1 ISOLATION AND EXPANSION OF NEURAL STEM CELLS 3 TRANSPLANTATION OF PROGENITOR CELLS 4 FACTORS THAT AFFECT DIFFERENTION OF RETINAL CELLS 7 EXPRESSION OF STRESS-RESPONSE PROTEINS 10 OXIDATIVE STRESS 13 PROTEOMICS 14 GENE ONTOLOGY 16 DISSERTATION ORGANIZATION 18 REFERENCES 18 CHAPTER 2.(More)
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