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Schizophrenia is characterized by lowered efficiency in distributed information processing, as indicated by research that identified a disrupted small-world functional network. However, whether the dysconnection manifested by the disrupted small-world functional network is reflected in underlying anatomical disruption in schizophrenia remains unresolved.(More)
The cingulo-opercular network (CON) is a newly defined control network responsible for various cognitive processes that have been consistently found to be impaired in schizophrenia. The aim of this study was to use functional connectivity magnetic resonance imaging (fcMRI) to test the hypothesis that schizophrenia is associated with functional disconnection(More)
—A generalized EEG-based Neural Fuzzy system to predict driver's drowsiness was proposed in this study. Driver's drowsy state monitoring system has been implicated as a causal factor for the safety driving issue, especially when the driver fell asleep or distracted in driving. However, the difficulties in developing such a system are lack of significant(More)
Schizophrenia is a debilitating mental disorder characterized by disturbances of thought and emotion as well as neurocognitive deficits. It is hypothesized that the core symptoms of schizophrenia arise from the inability to integrate neural processes segregated across distributed brain regions. Graph theory allows us to verify this hypothesis at large-scale(More)
Theta-burst transcranial magnetic stimulation could modulate cortical excitability and has the potential to treat refractory depression. However, there has been a lack of large randomized studies of the antidepressant efficacy of different forms of theta-burst stimulation, such as intermittent and continuous theta-burst stimulation. A randomized(More)
BACKGROUND Recent findings have indicated that patients with schizophrenia have altered cortico-cerebellar connectivity, but the nature of these network dysconnections remains unclear. AIMS We applied a network-based approach to investigate the functional connectivity (FC) of the cerebellum in patients with schizophrenia. METHODS Thirty-six patients(More)
Remission is the optimal outcome for major depressive disorder (MDD), but many patients do not improve appreciably despite treatment with medication. Treatment-resistant patients may experience deterioration in cognitive functions. Research has reported structural abnormalities in certain brain areas that may contribute to a poor clinical response. We(More)
BACKGROUND Repetitive transcranial magnetic stimulation (rTMS) has been developed as a novel tool for improving depression by delivering magnetic stimulation to the brain. However, the apparent effects of rTMS on depression have been varied in different studies. The aims of this study were to determine whether left dorsolateral prefrontal cortex rTMS can(More)
OBJECTIVE Tardive dyskinesia (TD) is a severe side effect of antipsychotics. While increasing evidence suggests that damaged brain microcircuitry of white matter (WM) is responsible for the clinical symptoms in schizophrenia, no reports of WM abnormality associated with TD were noted. METHOD Brain white matter abnormalities were investigated among 20(More)
The deficit of executive control is a core feature of schizophrenia, and as such, it provides hints for the neural signature of this devastating mental illness. The frontoparietal network (FPN) is a newly defined network important for various tasks requiring executive control. This study aims to investigate both the within- and between-network connectivity(More)