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  • Tullia Lindsten, Andrea J. Ross, +18 authors Craig B. Thompson
  • Medicine, Biology
  • Molecular cell
  • 2000 (First Publication: 1 December 2000)
  • Proapoptotic Bcl-2 family members have been proposed to play a central role in regulating apoptosis. However, mice lacking bax display limited phenotypic abnormalities. As presented here, bak(-/-)Expand
  • Weiwei. Zong, Tullia Lindsten, Andrea J. Ross, Grant R Macgregor, Craig B. Thompson
  • Biology, Medicine
  • Genes & development
  • 2001 (First Publication: 15 June 2001)
  • The BH3-only proteins Bim and Bad bind to the antiapoptotic Bcl-2 proteins and induce apoptosis in wild-type cells and cells from either bax(-/-) or bak(-/-) animals. In contrast, constitutivelyExpand