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A new source model for representing spatially distributed neural activity is presented. The signal of interest is modeled as originating from a patch of cortex and is represented using a set of basis functions. Each cortical patch has its own set of bases, which allows representation of arbitrary source activity within the patch. This is in contrast to(More)
A spatiotemporal framework for estimating trial-to-trial variability in evoked response (ER) data is presented. Spatial and temporal bases capture the aspects of the response that are consistent across trials, while the basis expansion coefficients represent the variable components of the response. We focus on the simplest case of constant spatiotemporal(More)
BACKGROUND The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used for detecting structure. However, it has not been adequately investigated whether the TW statistic is susceptible to type I error, especially in large, complex datasets.(More)
An extension of principal component analysis called ip-PCA has been proposed earlier for analyzing structure in genetic data. This non-parametric framework iteratively classifies individuals into subpopulations. However, it is prone to false positives when dealing with large datasets and mixed-type genetic markers. We address these shortcomings by(More)
Phenotypic differences among individuals of the same species are the result of a set of genetic variations which can be observed in the DNA sequence. To conduct a population genetic study, a high throughput genotyping platform such as Single Nucleotide Polymorphism (SNP) array is popularly used to obtain a large set of SNPs for each individual. However,(More)
Understanding genetic differences among populations is one of the most important issues in population genetics. Genetic variations, e.g., single nucleotide polymorphisms, are used to characterize commonality and difference of individuals from various populations. This paper presents an efficient graph-based clustering framework which operates iteratively on(More)
A weighing system in which a sensor is not mounted to a discharger especially in vertical filling gives rise to an excess of weight added to the given target of weight. In addition, the excess is not constant on account of some factors, such as vibration of the machine, flow of the substance, and cycle time of the system. These factors cause the surplus to(More)
This paper presents a spatiotemporal framework for estimating single-trial response latencies and amplitudes from evoked response magnetoencephalographic/electroencephalographic data. Spatial and temporal bases are employed to capture the aspects of the evoked response that are consistent across trials. Trial amplitudes are assumed independent but have the(More)