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Long Telomeres in Blood Leukocytes Are Associated with a High Risk of Ascending Aortic Aneurysm
Ascending aortic aneurysm is a connective tissue disorder. Even though multiple novel gene mutations have been identified, risk profiling and diagnosis before rupture still represent a challenge.… Expand
Elevated messenger RNA expression and plasma protein levels of osteopontin and matrix metalloproteinase types 2 and 9 in patients with ascending aortic aneurysms.
- Tuija Huusko, Tuire Salonurmi, +5 authors S. Kakko
- The Journal of thoracic and cardiovascular…
- 1 April 2013
OBJECTIVE Ascending aortic aneurysms result from a degenerative process in the aortic wall, characterized by the loss of smooth muscle cells and elastic fibers. We hypothesized that there would be… Expand
Effects of phosphatidylethanol on mouse adipocyte differentiation and expression of stearoyl-CoA desaturase 1.
- Tuija Huusko, M. Liisanantti, +4 authors M. Savolainen
- Medicine, Biology
- Alcoholism, clinical and experimental research
- 1 March 2007
BACKGROUND Phosphatidylethanol (PEth) is an aberrant phospholipid formed in vivo only in the presence of ethanol. In circulation PEth is associated with lipoproteins and is transferred from one… Expand
The fat mass and obesity-associated (FTO) gene variant rs9939609 predicts long-term incidence of cardiovascular disease and related death independent of the traditional risk factors
Abstract Objective and methods The impact of the rs9939609 FTO variant on cardiovascular events was investigated in the 19-year follow-up of subjects recruited to the OPERA study. Results A total of… Expand