Tsvetelina Gerasimova

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14 new transposable phages (TP) were isolated from approx. 200 clinical isolates of Pseudomonas aeruginosa. The frequent occurrence of TP of P. aeruginosa has been confirmed. There are at least two different groups of TP, namely, the group of D3112 and that of B3. The distinctive features of phages belonging to the groups are as follows: 1) low level of(More)
Plasmid DNA transduction with mini-D3112 delta H, deletion derivative of phage D3112, which lost the genes essential for phage growth but retained the sites required for transposition and packaging was studied. Unlike D3112, mini-D3112 delta H element can transduce plasmids and plasmid markers at frequencies of 10(-5)-10(-8) in rec+ cells of Pseudomonas(More)
Five phages (PH2, PH51, PH59, PH93 and PH132) which have some characteristics common with D3112, the transposable phage of Pseudomonas aeruginosa, were isolated from clinical P. aeruginosa isolates. The phages were distributed into 4 different immunity groups. The basic criteria used for selection of transposable phages have been: 1) Morphology of a phage(More)
Titanium dioxide nanoparticles, obtained using the sol-gel method and modified with organic solvents, such as acetone, acetonitrile, benzene, diethyl ether, dimethyl sulfoxide, toluene, and chloroform, were used as the filler of polydimethylsiloxane-based electrorheological fluids. The effect of electric field strength on the shear stress and yield stress(More)
Aroylhydrazones derived from salicylaldehyde are compounds with interesting biological properties including a high anticancer activity. Salicylaldehyde benzoylhydrazone (SBH) is an unusually potent inhibitor of DNA synthesis and cell growth in a variety of cultured human and rodent cells. Various derivatives of SBH have been synthesized in order to discover(More)
In recent decades, our attention is drawn to human-induced environmental changes and their potential threat to life on Earth through a growing number of mutagens and their effects on the biota. Genetic damage caused by these factors often have a durable effect that is manifested in later generations. The establishment of induced genetic damage in plants,(More)
Comparative assessment of in vitro and in vivo biological activity of anthracene-derived aminophosphonates, bis-aminophosphonates and poly(aminophosphonate)s, namely poly(oxyethylene aminophosphonate)s (4,5) and poly[oxyethylene aminophosphonate-co-H-phosphonate)]s, (6,7), were carried out in order to establish their value as potential drug candidates. The(More)