Tsuyoshi Yamauchi

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A new physiological index (&#x03BC;<sub>PA</sub>) is proposed to represent the autonomic nervous system (ANS) function. The index &#x03BC;<sub>PA</sub> is defined as the natural logarithm of the ratio between two different frequency components of the pulsatile amplitude of the photoplethysmogram (PPG) signal. The discrimination ability and the(More)
QRS morphological analysis in Holter electrocardiography has been developed using correlation coefficient methods. However, the accuracy of automated classification for QRS complexes, does not fully satisfy the clinical needs. In this paper, we propose a two-layered classification using self-organizing map (SOM). In the first layer, each beat is divided in(More)
In this study, an easy system for monitoring dynamic blood perfusion patterns and the pulse wave velocity (PWV) has been developed by processing video images of a human body to assess blood circulation for daily management of physical conditions or for detecting persons in poor physical condition in public places. The experiment suggested that this tool can(More)
1. The in vitro metabolism of alectinib, a potent and highly selective oral anaplastic lymphoma kinase inhibitor, was investigated. 2. The main metabolite (M4) in primary human hepatocytes was identified, which is produced by deethylation at the morpholine ring. Three minor metabolites (M6, M1a, and M1b) were also identified, and a minor peak of(More)
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