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  • T Katsuta
  • 1997
Local cerebral blood flow (LCBF) was measured using the [14C] iodoantipyrine method in 76 discrete brain regions in spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY) of 4 months old (young-adult) and 16-17 months old (aged). Compared with the young-adult WKY, in both the young-adult and aged SHR, LCBF was reduced in scattered(More)
BACKGROUND Although acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) is a well known clinical condition, predicting risk factors remain unknown. We evaluated the frequency, risk factors and impact on survival of AE-IPF. METHODS We retrospectively studied patients diagnosed with IPF based on the criteria of the ATS/ERS consensus statement and(More)
The purpose of this study was to evaluate the efficacy and safety of volumetric modulated arc therapy (VMAT) after extrapleural pneumonectomy (EPP) in patients with malignant pleural mesothelioma (MPM). A total of 15 patients who received VMAT after EPP were enrolled. All patients were males, and the median age was 67 years (Stage IB in two, II in six, and(More)
The chronic toxicity study of mofezolac (N-22), a new developed analgesic and anti-inflammatory agent, was carried out in beagle dogs by oral administration of the test compound at dose levels of 1, 3, 6 and 12 mg/kg once daily for 52 weeks. The recovery study was also carried out by withdrawal for 5 weeks. 1. No death occurred during the administration and(More)
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