Tsung Lung Yang

Learn More
PURPOSE An earlier phase II trial of paclitaxel in patients with metastatic nasopharyngeal carcinoma (NPC) demonstrated a response rate of 22%. Hence we proceeded to study the combination of paclitaxel and carboplatin in these patients. PATIENTS AND METHODS The 21-day regimen was as follows: i.v. paclitaxel 175 mg/m2 over three hours preceded by standard(More)
BACKGROUND The objective of the current study was to describe the survival of nasopharyngeal carcinoma (NPC) patients in Singapore, verify the prognostic value of the revised 1997 TNM staging system, and develop a multivariate prognostic model for NPC. In addition, the authors also examined the prognostic value of characteristics of lymph node spread and(More)
BACKGROUND Intracranial germ cell tumours (IGCT) are rare. We present our experience in Therapeutic Radiology Department, National Cancer Centre, Singapore. METHODS A retrospective study was conducted through case notes review on 25 patients with IGCT referred between January 1988 and January 1999. RESULTS The median age at diagnosis was 13 years (range(More)
7 3 4 $ , ) H H 6 > 2 3 4 , ! , 1 ! " 1 B G ) G ! " " $ # F <B 324 : $ ) % " : H ) F & # $ %&' ! ( 3-4 # F H H = F I : : > ; / )*** " * ++ 55 3'4 ) : 1 = : 9 &, J 2 384 G , F " " ) F 1 > F > E / 9 B / 9* > , ; # ! F 1 F , -+. '2J 304 " F 1 G , &/ J5 354 H H H ! A9 F < H ! + 2 3J4 H H ? ) H / ; B E ) 1 G , -&. -00 3 4 # / ) ) 0 ! " %. J 3 4 : ? ? 9 I < " &(More)
With effect from July 1987 CT-scans of the nasopharynx became routinely available in the staging of nasopharyngeal cancer (NPC) in our department. Eighty-four evaluable cases during these first six months were studied and the results at a median follow-up period of 34 months revealed that 74% were alive at 2 years. The local relapse rate were 4% for T1; 10%(More)
This is a report analysing the patient profile and survival results in 270 patients with nasopharyngeal carcinoma treated with radiation therapy between July 1987 and December 1988. The patients had a median age of 52.6 months, and a male-female ratio of 2.5:1. Ninety-four percent of patients were Chinese. The commonest presentation was that of a neck mass(More)
A malignant transformation or a tumor rupture is a rare complication of ovarian mature cystic teratoma (MCT). A tumor rupture in a malignant-transformed MCT has never been reported in the literature. We present the CT images of a 39-year-old woman showing a large, predominantly cystic mass in the lower abdomen, with fat-fluid-level ascites. A(More)
Orbital lymphoma is a rare presentation of non-Hodgkin's lymphoma. Treatment with radiotherapy is well-established. Twenty cases of orbital lymphoma treated at the Singapore General Hospital with radiation therapy were reviewed. All patients had improvement of their initial presenting symptoms and complete remission after radiation. Long-term local control(More)
INTRODUCTION We investigated the relationship between frequency of exacerbation and duration and change in functional status, as measured by the BODE index in chronic obstructive pulmonary disease (COPD) patients. METHODS This was a longitudinal cohort study of 56 patients with moderate to severe COPD. Body mass index, spirometry, Modified Medical(More)
BACKGROUND Any malignancy has the propensity to metastasize to skin. The frequency of skin metastases vary in different tumors and occur in about 0.7% to 10% of all patients diagnosed with cancer. It is rare in nasopharyngeal carcinoma. METHOD Three cases of relapsed nasopharyngeal carcinoma with diffuse dermal involvement were described. Their clinical(More)