Tsuneyoshi Suzuki

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Characterization and release profiles of commercial dexamethasone dipropionate (DDP) from an innovator and 2 generic ointments (Methaderm (IM), Promethasone (GP), and Mainvate (GM)) and their admixtures with heparinoid ointment (Hirudoid Soft) were investigated. The admixtures were prepared using 2 mixing methods (slab or rotation/revolution mixer).(More)
The aim of this study was to investigate the existence of the stretch activated ion channels in single Merkel cell using microfluorimetric techniques. Single Merkel cells were dissociated enzymatically from the touch domes in the cheek pouch mucosa of 4-8 week old golden hamsters. They were loaded with calcium (Ca2+) fluorescent indicator fura-2/AM. The(More)
It is well known that nutritional status during the fetal and/or lactation period is important for the development of the central nervous system (CNS). In contrast, the effect of malnutrition on postweaning development has not yet been thoroughly investigated. In the present study, we analyzed the behavioral and neuroanatomical effects of protein(More)
Tebanicline (ABT-594), an analogue of epibatidine, exhibits potent antinociceptive effects and high affinity for the nicotinic acetylcholine receptor in the central nervous system. We assessed whether tebanicline exerts an effect on various noxious stimuli and mediates the nicotine receptor or opioid receptor through stimulation. The antinociceptive effects(More)
We observed the surface morphological structures of 60 mg tablets of Loxonin, Loxot, and Lobu using scanning electron microscope (SEM) and atomic force microscope (AFM) to evaluate the dissolution rates. We found a significant difference among the initial dissolution rates of the three kinds of loxoprofen sodium tablets. Petal forms of different sizes were(More)
  • Takeshi Asanuma, Masahiro Nakamura, +26 authors Noritaka Wang
  • Journal of Medical Ultrasonics
  • 2014
Akimoto, Shin Akiyama, Iwaki Arita, Takeshi Asanuma, Toshihiko Bandou, Hiroko Bonilla-Musoles, Fernando Fujimoto, Shinichi Fujimoto, Taketoshi Fujimoto, Yasuhisa Fukae, Jun Fukaya, Yasushi Gouda, Akiko Hamaguchi, Hirotoshi Hata, Jiro Hata, Toshiyuki Hayashi, Satoshi Hirano, Yutaka Hirata, Kenichirou Hirooka, Yoshiki Ibuki, Eri Ichihashi, Kou Ichizuka,(More)
We investigated whether postweaning protein malnutrition (PM) affects serotonergic systems. Mice were fed a PM diet or normal protein (control) diet from weaning (21 d of age). Twenty days later, we tested for behavioral effects of the selective serotonin (5-HT)(1A) receptor agonist 8-hydroxy-N,N-dipropyl-2-aminoteralin (8-OH-DPAT) and the 5-HT releaser(More)