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The Purkinje fibers are located in the ventricular walls of the heart, just beneath the endocardium and conduct excitation from the right and left bundle branches to the ventricular myocardium. Recently, anatomists succeeded in photographing the Purkinje fibers of a sheep, which clearly showed the mesh structure of the Purkinje fibers. In this study, we(More)
  • Shigeru 0wada, Takenori yao, Tsunetoyo Namba, Takashi shihara, Takanori 1keda
  • 2007
Takanori 1keda2, and Kazuo ~ a k a z a w a " ~ Chapter Overview. We present an electrophysiological heart simulator equipped with sketchy 3-D modeling interface. It has been tedious and time-consuming to create the shape of heart for use it in the simulator. In this study, we developed a new simulator that is combined with a sketch-based 3-D modeling(More)
RATIONALE Electrogram-based catheter ablation, targeting complex fractionated atrial electrograms (CFAEs), is empirically known to be effective in halting persistent/permanent atrial fibrillation (AF). However, the mechanisms underlying CFAEs and electrogram-based ablation remain unclear. OBJECTIVE Because atrial fibrosis is associated with(More)
  • Ayaka Kawase, Takanori Ikeda, +5 authors Hironori Hirai
  • 2003
BACKGROUND This study aimed to assess the effects of pilsicainide, a pure sodium channel blocker, on electrophysiological action and wavefront dynamics during atrial fibrillation (AF). METHODS AND RESULTS In a newly developed model of isolated, perfused, and superfused canine atria (n=12), the right and left endocardia were mapped simultaneously by use of(More)
INTRODUCTION It has been reported that electrical stimulation can control spiral wave (SW) reentry. However, previous research does not account for the effects of stimulus-induced virtual electrode polarization (VEP) and the ensuing cathode-break (CB) excitation. The aim of the present study was to examine the interaction of VEP with SW reentry in a(More)
BACKGROUND AND PURPOSE Preoperative identification of plaque vulnerability may allow improved risk stratification for patients considered for carotid endarterectomy. The present study aimed to determine which plaque imaging technique, cardiac-gated black-blood fast spin-echo, magnetization-prepared rapid acquisition of gradient echo, source image of 3D(More)
We present an electrophysiological heart simulator with schematic 3-D modeling interface. It has been tedious and troublesome interactive work to create a shape of heart for using it in the simulator. In our developing system, as soon as changing the shape of heart easily and quickly, we can execute the simulation and the visualiza-tion of the result. Our(More)
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