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Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-β signaling
TLDR
A SRC-mediated signaling cascade that leads to the relocalization of ER chaperones to the cell surface and a mechanism whereby GRP78 counteracts the tumor-suppressor effect of TGF-β are uncovered. Expand
Shapechanger: Environments for Transfer Learning
We present Shapechanger, a library for transfer reinforcement learning specifically designed for robotic tasks. We consider three types of knowledge transfer---from simulation to simulation, fromExpand