Tsair-Fwu Lee

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BACKGROUND With the advances in modern radiotherapy (RT), many patients with head and neck cancer (HNC) can be effectively cured, and their health-related quality of life (HR-QoL) has become an important issue. In this study, we evaluated the prognosticators of HR-QoL in a large cohort of HNC patients, with a focus on the result from technological advances(More)
PURPOSE The aim of this study was to develop a multivariate logistic regression model with least absolute shrinkage and selection operator (LASSO) to make valid predictions about the incidence of moderate-to-severe patient-rated xerostomia among head and neck cancer (HNC) patients treated with IMRT. METHODS AND MATERIALS Quality of life questionnaire(More)
Given the poor prognosis of esophageal cancer and the invasiveness of combined modality treatment, improved prognostic scoring systems are needed. We developed a fuzzy logic-based system to improve the predictive performance of a risk score based on the serum concentrations of C-reactive protein (CRP) and albumin in a cohort of 271 patients with esophageal(More)
PURPOSE To analyze of survival curve and toxicity outcomes for patients treated for nasopharyngeal carcinoma (NPC) by intensity-modulated radiotherapy (IMRT) delivered by helical TomoTherapy (HT). MATERIALS AND METHODS Since May 2006, 72 patients with primary NPC were treated. In 67 cases PET-CT was used to help delineate the gross tumor volume (GTV); in(More)
The introduction of adaptive image-guided radiotherapy (ART) has contributed to the rapid accumulation of spatiotemporal medical image data, often making it difficult to consolidate information on a single patient. For oncology patients, the lack of data integration can negatively impact on patient care. We developed a volume visualization system with(More)
We study the problem of dynamically scheduling a set of period stage control tasks controlling a set of large air conditioner loads (ACLs). To be able to solve the scheduling problem for realistic on-line cases, we utilize the technique of relaxed dynamic programming (RDP) algorithm to generate an optimal or near optimal daily control scheduling for ACLs(More)
PURPOSE An analytical and experimental study of split shape dose calculation correction by adjusting the position of the on-axis round leaf end position is presented. We use on-axis corrected results to predict off-axis penumbra region dosimetric performance in an intensity-modulated radiation therapy treatment planning system. MATERIALS AND METHODS The(More)
We investigated the incidence of moderate to severe patient-reported xerostomia among nasopharyngeal carcinoma (NPC) patients treated with helical tomotherapy (HT) and identified patient- and therapy-related factors associated with acute and chronic xerostomia toxicity. The least absolute shrinkage and selection operator (LASSO) normal tissue complication(More)
PURPOSE Dosimetric evaluations of single and multiple liver tumours performed using intensity-modulated helical tomotherapy (HT) were quantitatively investigated. Step-and-shoot intensity-modulated radiotherapy (SaS-IMRT) was used as a benchmark. METHODS Sixteen patients separated into two groups with primary hepatocellular carcinomas or metastatic liver(More)