Tsai-Rong Chang

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Sensitivity of central auditory neurons to frequency modulated (FM) sound is often characterized based on spectro-temporal receptive field (STRF), which is generated by spike-trigger averaging a random stimulus. Due to the inherent property of time variability in neural response, this method erroneously represents the response jitter as stimulus jitter in(More)
Knowledge on the trigger features of central auditory neurons is important in the understanding of speech processing. Spectro-temporal receptive fields (STRFs) obtained using random stimuli and spike-triggered averaging allow visualization of trigger features which often appear blurry in the time-versus-frequency plot. For a clearer visualization we have(More)
Frequency modulation (FM) is an important building block of communication signals for animals and human. Attempts to predict the response of central neurons to FM sounds have not been very successful, though achieving successful results could bring insights regarding the underlying neural mechanisms. Here we proposed a new method to predict responses of(More)
A gas chromatographic combustion isotope ratio mass spectrometric (GC/C/IRMS) method was used for studying the incorporation of exogenous testosterone enanthate into excreted urinary 5 alpha- and 5 beta-androstane-3 alpha, 17 beta-diols. A multistep but straightforward work-up procedure produced a simple GC chromatogram of urinary steroid acetates composed(More)
The basis of a potential method for confirming intake of four natural androgens (testosterone, epitestosterone, dihydrotestosterone, and dehydroepiandrosterone is presented. The method relies on isolating from urine a steroid fraction containing androstenediol and androstanediol metabolites of these natural steroids and analyzing their 13C content by gas(More)
Frequency modulation (FM) is an important building block of complex sounds that include speech signals. Exploring the neural mechanisms of FM coding with computer modeling could help understand how speech sounds are processed in the brain. Here, we modeled the single unit responses of auditory neurons recorded from the midbrain of anesthetized rats. These(More)
Spectro-temporal receptive fields (STRFs) are commonly used to characterize response properties of central auditory neurons and for visualizing 'trigger features'. However, trigger features in STRF maps typically have a blurry appearance. Therefore it is unclear what details could be embedded in them. To investigate this, we developed a new method called(More)
Time variance of sound energy is an important feature of communication signals that include speech [1]. One of the two major components is time variance in frequency or frequency modulation (FM). Substantial numbers of neurons have been found along the ascending auditory pathways responsive to FM but not pure tone stimuli (FM sensitive cells), starting at(More)