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  • Janet Martha Blatny, Trygve Brautaset, Hanne Cecilie Winther-Larsen, Kristin Haugan, Svein Valla
  • Medicine, Biology
  • Applied and environmental microbiology
  • 1997 (First Publication: 1 February 1997)
  • The plasmid vectors described in this report are derived from the broad-host-range RK2 replicon and can be maintained in many gram-negative bacterial species. The complete nucleotide sequences of allContinue Reading
  • Trygve Brautaset, Olga N. Sekurova, +4 authors Sergey B Zotchev
  • Biology, Medicine
  • Chemistry & biology
  • 2000 (First Publication: 1 June 2000)
  • BACKGROUND The polyene macrolide antibiotic nystatin produced by Streptomyces noursei ATCC 11455 is an important antifungal agent. The nystatin molecule contains a polyketide moiety represented by aContinue Reading
  • Janet Martha Blatny, Trygve Brautaset, Hanne Cecilie Winther-Larsen, P Karunakaran, Svein Valla
  • Biology, Medicine
  • Plasmid
  • 1997 (First Publication: 1 July 1997)
  • This report describes the construction and use of improved broad-host-range expression vectors based on the previously constructed pJB137 and pJB653 plasmids (Blatny et al., 1997). These vectorsContinue Reading
  • Olga N. Sekurova, Trygve Brautaset, +6 authors Sergey B Zotchev
  • Medicine, Biology
  • Journal of bacteriology
  • 2004 (First Publication: 1 March 2004)
  • Six putative regulatory genes are located at the flank of the nystatin biosynthetic gene cluster in Streptomyces noursei ATCC 11455. Gene inactivation and complementation experiments revealed thatContinue Reading
  • T. M. B. Heggeset, Anne Helene Krog, Simone Balzer, Alexander Wentzel, T. E. Ellingsen, Trygve Brautaset
  • Medicine, Biology
  • Applied and Environmental Microbiology
  • 2012 (First Publication: 18 May 2012)
  • ABSTRACT Bacillus methanolicus can utilize methanol as its sole carbon and energy source, and the scientific interest in this thermotolerant bacterium has focused largely on exploring its potentialContinue Reading
    The natural plasmid pBM19 carries the key mdh gene needed for the oxidation of methanol into formaldehyde by Bacillus methanolicus. Five more genes, glpX, fba, tkt, pfk, and rpe, with deduced rolesContinue Reading
  • Simone Balzer, Veronika Kuchárová, Judith A Megerle, Rahmi Lale, Trygve Brautaset, Svein Valla
  • Biology, Medicine
  • Microbial Cell Factories
  • 2013 (First Publication: 18 March 2013)
  • BackgroundProduction of recombinant proteins in bacteria for academic and commercial purposes is a well established field; however the outcomes of process developments for specific proteins are stillContinue Reading
  • Anne Helene Krog, T M B Heggeset, +5 authors Trygve Brautaset
  • Medicine, Biology
  • PloS one
  • 2013 (First Publication: 19 March 2013)
  • Bacillus methanolicus can utilize methanol as the sole carbon source for growth and it encodes an NAD+-dependent methanol dehydrogenase (Mdh), catalyzing the oxidation of methanol to formaldehyde.Continue Reading