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Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans.
- I. Rafter, Truls Gråberg, +10 authors B. Glinghammar
- Biology, Medicine
- International journal of molecular medicine
- 1 November 2012
Serum alanine aminotransferase (ALT) is used as a clinical marker to detect hepatic damage and hepatoxicity. Two isoforms of ALT have been identified, ALT1 and ALT2, which have identical enzymatic… Expand