Troy A Young

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Acute mountain sickness (AMS) is a common condition that affects people that ascend too rapidly to high altitude. It is typically assessed with the Lake Louise AMS Self-report Score (LLSelf) that uses a categorical numeric rating scale to answer five questions addressing AMS-related symptoms, such as headache. A 100-mm visual analog scale (VAS) is commonly(More)
Active sniffing in rodents at theta frequency during exploratory behavior has been hypothesized to enhance odorant access to the receptor sheet and to evoke activity patterns in olfactory and limbic structures which facilitate induction of synaptic plasticity. The present results demonstrate a third potential consequence of theta frequency sniffing --(More)
OBJECTIVE The interaction of 15 variables representing physical characteristics, previous altitude exposure, and ascent data was analyzed to determine their contribution to acute mountain sickness (AMS). METHODS Questionnaires were obtained from 359 volunteers upon reaching the summit of Mt Whitney (4419 m). Heart rate and arterial oxygen saturation were(More)
Polyglutamine expansions in proteins are implicated in at least eight inherited neurodegenerative disorders, including Huntington's disease. These mutant proteins can form aggregates within the nucleus and processes of neurons possibly due to misfolding of the proteins. Polyglutamine aggregates are ubiquitinated and sequester molecular chaperone proteins(More)
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