Troels Bo Thomsen

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OBJECTIVES To develop a new methodology to systematically compare evidence across diverse risk markers for coronary heart disease and to compare this evidence with guideline recommendations. DESIGN "Horizontal" systematic review incorporating different sources of evidence. DATA SOURCES Electronic search of Medline and hand search of guidelines. Study(More)
The ability to harness the RNA interference (RNAi) mechanism as a potential potent therapeutic has attracted great interest from academia and industry. Numerous preclinical and recent clinical trials have demonstrated the effectiveness of RNAi triggers such as synthetic small interfering RNA (siRNA). Chemical modification and delivery technologies can be(More)
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