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Cortical forces and CDC-42 control clustering of PAR proteins for Caenorhabditis elegans embryonic polarization
Cell polarization enables zygotes to acquire spatial asymmetry, which in turn patterns cellular and tissue axes during development. Local modification in the actomyosin cytoskeleton mediates spatialExpand
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Cortical forces and CDC-42 control clustering of PAR proteins for C. elegans embryonic polarization
membrane potential. drp1 mutant PFCs also showed increased Ras and phosphorylated ERK and loss of Notch mediated differentiation. In order to dissect out the distinct roles of metabolism andExpand
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Forceful patterning in mouse preimplantation embryos.
The generation of a functional organism from a single, fertilized ovum requires the spatially coordinated regulation of diverse cell identities. The establishment and precise arrangement ofExpand
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