Triantafyllia Koletsa

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BACKGROUND CONTEXT Spinal epidural plasmacytomas are very rare and are usually localized in the cervicothoracic and lumbar spines. PURPOSE To present the first case of cervical dural plasmacytoma and discuss the treatment options for this entity. STUDY DESIGN Case report and review of the literature. METHODS A 45-year-old man presented with gradually(More)
The serine/threonine kinase B-Raf plays a key role in the Ras/Raf/MEK/ERK pathway that relays extracellular signals for cell proliferation and survival. Several types of human malignancies harbor activating BRAF mutations, most frequently a V600E substitution. The epidermal growth factor receptor (EGFR), a transmembrane tyrosine kinase (TK) receptor that(More)
Primary cutaneous plasmacytoma is defined as monoclonal proliferation of plasma cells that arises primarily in the skin without evidence of systemic disease. We present an extremely rare case of a young adult diagnosed with solitary plasmacytoma. A 20-year-old woman presented with a pruritic erythematosquamous indurated plaque on the inner aspect of her(More)
Sir, Synovial sarcoma (SS) is the fourth most common type of soft-tissue sarcoma, and usually occurs in the paraarticular regions of the extremities [10]. Despite its name, this tumor is uncommon in joint cavities, while it may be encountered in areas with no apparent relationship to synovial structures, such as the parapharyngeal region, abdominal wall,(More)
The Androgen Receptor (AR) is a potential prognostic marker and therapeutic target in breast cancer. We evaluated AR protein expression in high-risk breast cancer treated in the adjuvant setting. Tumors were subtyped into luminal (ER+/PgR±/AR±), molecular apocrine (MAC, [ER-/PgR-/AR+]) and hormone receptor negative carcinomas (HR-negative, [ER-/PgR-/AR-]).(More)
Mesectodermal leiomyoma of the ciliary body is a rare benign tumor with double (muscular and neural) differentiation. This neoplasm is considered to originate from the ciliary body smooth muscle, a neural crest derivative. We report a case of mesectodermal leiomyoma of the right eye occurring in a 53-year-old woman, who presented with significant decrease(More)
Dear Editors: Ciliated hepatic foregut cyst (CHFC) has previously been considered to be a rare lesion. However, in the last 15 years, the advent of radiological procedures has resulted in the publication of a number of case reports as well as three case series [1, 3, 4], suggesting that this entity has been underreported because it is usually asymptomatic.(More)
BRCA1 (B), ERCC1 (E), RRM1 (R) and TYMS (T) mRNA expression has been extensively studied with respect to NSCLC patient outcome upon various chemotherapy agents. However, these markers have not been introduced into clinical practice yet. One of the reasons seems to be lack of a standard approach for the classification of the reported high/low mRNA(More)
Angiomatoid fibrous histiocytoma is an unusual soft tissue tumor, mostly arising in the subcutaneous fibro-adipose tissue of children and young adults and measuring a few centimeters in greatest dimension. Reported herein is a unique case of angiomatoid fibrous histiocytoma containing epithelium-lined cystic structures. This large tumor (12 cm) was located(More)
The HER2 gene has been established as a valid biological marker for the treatment of breast cancer patients with trastuzumab and probably other agents, such as paclitaxel and anthracyclines. The TOP2A gene has been associated with response to anthracyclines. Limited information exists on the relationship of HER2/TOP2A gene status in the presence of(More)