Tri Thanh Nguyen Le

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BACKGROUND This study evaluated the efficacy and the complications associated with the use of the covered Wallstent in the setting of unresectable malignant biliary obstruction. METHODS Between March 2001 and January 2003, all patients with distal malignant biliary obstruction that required drainage were treated with a covered Wallstent. Every 2 months,(More)
The advent of precision medicine in non-small cell lung cancer has remarkably altered the direction of research and improved clinical outcomes. The identification of molecular subsets with differential response to targeted therapies began with the identification of epidermal growth factor receptor mutated tumors in subsets of non-small cell lung cancer(More)
BACKGROUND The self-expandable metallic stent is increasingly being used for management of malignant biliary strictures. In certain clinical situations, it also may be an alternative treatment for benign strictures. The ability to remove a metallic stent would be advantageous to the management of many biliary strictures, regardless of etiology. METHODS(More)
AIM To determine the relationship between accommodative amplitude and central lens thickness/equatorial lens diameter (CLT/ELD) ratio in vertebrates. METHODS Midsagittal sections of lenses from fixed, post mortem eyes from 125 different vertebrate species were photographed. Their CLT/ELD ratios were correlated with independently published measurements of(More)
We present rate constants and product branching ratios for the reactions of FeOx+ (x = 0-4) with ozone at 500 K. Fe+ is observed to react with ozone at the collision rate to produce FeO+ + O2. The FeO+ in turn reacts with ozone at the collision rate to yield both Fe+ and FeO2+ product channels. Ions up to FeO4+ display similar reactivity patterns.(More)
BACKGROUND Lip metastases are rare clinical events that are frequently mistaken for other diagnoses. For sarcomatoid lung carcinoma, a rare histologic variant of non-small cell lung cancer, the incidence and pattern of cutaneous spread is poorly understood. CASE PRESENTATION We present a case of a 79-year-old African American man with a rapidly(More)
Resistance to EGFR kinase inhibitors appears to be invariable in the treatment of non-small cell lung cancer. Several mechanisms have been described. Here, we report the first case of histologic transformation of EGFR mutant lung adenocarcinoma without prior exposure to EGFR inhibition.
[reaction: see text] The cross metathesis reactivities of alpha-methylene-gamma-butyrolactone and an alpha-methylene-delta-lactone have been investigated. alpha-Methylene-gamma-butyrolactone undergoes rapid and efficient olefin isomerization in the presence of second-generation metathesis catalysts. However, cross metathesis can be achieved with the(More)