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  • Kathleen M. Meneely, Trey A Ronnebaum, Andrew P. Riley, Thomas E. Prisinzano, Audrey L Lamb
  • Chemistry, Medicine
  • Biochemistry
  • 2016 (First Publication: 15 September 2016)
  • Thiazolinyl imine reductases catalyze the NADPH-dependent reduction of a thiazoline to a thiazolidine, a required step in the formation of the siderophores yersiniabactin (Yersinia spp.) andContinue Reading
  • Jeffrey S McFarlane, Trey A Ronnebaum, Kathleen M. Meneely, Annemarie S. Chilton, Aron W Fenton, Audrey L Lamb
  • Medicine, Biology
  • Acta crystallographica. Section F, Structural…
  • 2019 (First Publication: 1 June 2019)
  • Human liver pyruvate kinase (hLPYK) converts phosphoenolpyruvate to pyruvate in the final step of glycolysis. hLPYK is allosterically activated by fructose-1,6-bisphosphate (Fru-1,6-BP). TheContinue Reading
  • Patrick N. Blank, Arnold Barnett, +4 authors J A Himmelberger
  • Medicine, Chemistry
  • Acta crystallographica. Section D, Structural…
  • 2020 (First Publication: 29 May 2020)
  • Archaea are uniquely adapted to thrive in harsh environments, and one of these adaptations involves the archaeal membrane lipids, which are characterized by their isoprenoid alkyl chains connectedContinue Reading
  • Trey A Ronnebaum, Kushol Gupta, David W Christianson
  • Biology, Medicine
  • Journal of structural biology
  • 2020 (First Publication: 21 January 2020)
  • The unusual diterpene (C20) synthase copalyl diphosphate synthase from Penicillium verruculosum (PvCPS) is the first bifunctional terpene synthase identified with both prenyltransferase and class IIContinue Reading