• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • T W Fischer, Trevor W. Sweatman, I. Semak, Robert M. Sayre, Jacobo Wortsman, Andrzej Słomiński
  • Biology, Medicine
  • FASEB journal : official publication of the…
  • 2006 (First Publication: 1 July 2006)
  • Melatonin, which can be produced in the skin, exerts a protective effect against damage induced by UV radiation (UVR). We have investigated the effect of UVB, the most damaging component of UVR, onContinue Reading
  • T W Fischer, Michał A. Żmijewski, +4 authors A T Slominski
  • Biology, Medicine
  • International journal of oncology
  • 2006 (First Publication: 1 September 2006)
  • Melatonin has been shown to have oncostatic effects on malignant melanoma in vitro and in vivo. We studied the growth suppressive effects of melatonin over a wide range of concentrations in fourContinue Reading
  • Leonard Lothstein, Luydmila Savranskaya, Christina M. Barrett, Mervyn Israel, Trevor W. Sweatman
  • Biology, Medicine
  • Anti-cancer drugs
  • 2006 (First Publication: 1 June 2006)
  • Unlike nuclear-targeted anthracyclines, the extranuclear-targeted doxorubicin congener, N-benzyladriamycin-14-valerate (AD 198), does not interfere with normal topoisomerase II activity, but binds toContinue Reading
  • Ganesh R. Panta, Swayamjot Kaur, +6 authors Marcello Arsura
  • Biology, Medicine
  • Molecular and cellular biology
  • 2004 (First Publication: 1 March 2004)
  • We have identified a novel pathway of ataxia telangiectasia mutated (ATM) and DNA-dependent protein kinase (DNA-PK) signaling that results in nuclear factor kappaB (NF-kappaB) activation andContinue Reading
  • J Brent Roaten, Marcelo G Kazanietz, +5 authors Trevor W. Sweatman
  • Biology, Medicine
  • Molecular cancer therapeutics
  • 2002 (First Publication: 1 May 2002)
  • Anthracycline antibiotics like doxorubicin (DOX) are known to exert their antitumor effects primarily via DNA intercalation and topoisomerase II inhibition. By contrast, the noncross-resistantContinue Reading
  • Leonard Lothstein, Helen M. Wright, Trevor W. Sweatman, Mervyn Israel
  • Biology, Medicine
  • Oncology research
  • 1992
  • N-Benzyladriamycin-14-valerate (AD 198) is a highly hydrophobic analogue of Adriamycin (ADR) which can circumvent multidrug resistance (MDR) in various cell lines. Unlike ADR, AD 198 avoids extrusionContinue Reading