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  • Elizabeth M. Tunbridge, David M Bannerman, Trevor Sharp, Philip J Harrison
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 2004 (First Publication: 9 June 2004)
  • The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene affects activity of the enzyme and influences performance and efficiency of the prefrontal cortex (PFC); however,Continue Reading
  • Mihály Hajós, Chris Richards, Andrea D Székely, Trevor Sharp
  • Medicine, Biology
  • Neuroscience
  • 1998 (First Publication: 1 June 1998)
  • In this study we utilized electrophysiological and pathway tracing methods to investigate the projections from the medial prefrontal cortex to the midbrain raphe nuclei of the rat. Initial pathwayContinue Reading
  • Laura W. Harris, Trevor Sharp, Jane Gartlon, Declan N. C. Jones, Paul J. Harrison
  • Biology, Medicine
  • The European journal of neuroscience
  • 2003 (First Publication: 1 September 2003)
  • Brief N-methyl-D-aspartate (NMDA) receptor blockade in neonatal rats has been reported to increase neuronal apoptosis. We replicated this finding using MK-801 (0.5 mg/kg) administered twice onContinue Reading
  • Sarah E Gartside, V Umbers, Mihály Hajós, Trevor Sharp
  • Chemistry, Medicine
  • British journal of pharmacology
  • 1995 (First Publication: 1 July 1995)
  • 1. The acute inhibitory effect of selective 5-hydroxytryptamine (serotonin) reuptake inhibitors (SSRIs) on 5-HT neuronal activity may offset their ability to increase synaptic 5-HT in the forebrain.Continue Reading
  • M. E. Walton, James Groves, +4 authors David M Bannerman
  • Medicine, Biology
  • The European journal of neuroscience
  • 2009 (First Publication: 1 April 2009)
  • Both the anterior cingulate cortex (ACC) and mesolimbic dopamine, particularly in the nucleus accumbens (NAc), have been implicated in allowing an animal to overcome effort constraints to obtainContinue Reading