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Nature-Guided Synthesis of Advanced Bio-Lubricants
Design of environmentally friendly lubricants derived from renewable resources is highly desirable for many practical applications. Here, Orychophragmus violaceus (Ov) seed oil is found to haveExpand
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Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential
Prostate epithelial cells control the potency and availability of androgen hormones in part by inactivation and elimination. UDP-glucose dehydrogenase (UGDH) catalyzes the NAD+-dependent oxidation ofExpand
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Abstract C41: Altered control of intracellular androgen availability by glucuronidation contributes to loss of androgen dependence in prostate tumor cells
Locally advanced and metastatic cancers are frequently treated by androgen deprivation therapy. Tumors that recur despite this treatment, termed castration resistant prostate cancer, are highlyExpand