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This study proposed that attenuated expression of inflammatory factors is an underlying mechanism driving the repeated-bout effect (rapid adaptation to eccentric exercise). We investigated changes in mRNA levels and protein localization of inflammatory genes after two bouts of muscle-lengthening exercise. Seven male subjects performed two bouts of lower(More)
In this study, we examined the time course of changes in running economy following a 30-min downhill (-15%) run at 70% peak aerobic power (VO2peak). Ten young men performed level running at 65, 75, and 85% VO2peak (5 min for each intensity) before, immediately after, and 1 - 5 days after the downhill run, at which times oxygen consumption (VO2), minute(More)
This study investigated the hypothesis that the protective effect conferred by a low-intensity eccentric exercise against maximal eccentric exercise would not last more than a week. Untrained men (21.3 ± 1.6 years) were allocated into either a control or one of four repeated bout groups (n = 13 per group). The repeated bout groups performed 30 low-intensity(More)
In this study, we tested the hypothesis that running economy assessed at a high intensity [e.g. 90% maximal oxygen capacity (VO2(max))] would be affected more than at a lower intensity (e.g. 70% VO2(max)) after downhill running. Fifteen untrained young men performed level running at 70, 80, and 90% VO2(max) (5 min for each intensity) before and 2 and 5 days(More)
Since little is known about the repeated bout effect of more than two eccentric exercise bouts, this study compared muscle damage responses among four exercise bouts. Fifteen young (21.8 +/- 1.9 years) men performed four bouts of 30 maximal isokinetic eccentric contractions of the elbow flexors every 4 weeks. Maximal voluntary elbow flexion isometric and(More)
This study investigated the time wise protective effect conferred by two maximal voluntary isometric contractions (2MVCs) at 20° elbow flexion on muscle damage induced by 30 maximal isokinetic (60° s−1) eccentric contractions of the elbow flexors (MaxECC). Sixty-five young untrained men were randomly assigned to a control group that did not perform 2MVCs,(More)
This study investigated whether the second eccentric exercise performed 3 days after the initial bout would exacerbate muscle damage and retard the recovery. Fifty-one athletes performed 30 eccentric actions of the elbow flexors using a dumbbell weighted 100% of the maximal isometric force (MIF) at the elbow joint angle of 90 degrees (ECC1). Three days(More)
This study compared changes in indirect markers of muscle damage following eccentric exercise of the elbow flexors among the exercises consisting of different number of eccentric actions. Sixty male athletes were placed into one of the six groups (n=10 per group) based on the number of eccentric actions for the first (ECC1) and second exercise bouts (ECC2).(More)
This study investigated whether low-intensity eccentric contractions of the knee extensors would attenuate the magnitude of muscle damage induced by maximal eccentric exercise of the same muscle performed 7 days later using elderly individuals. Healthy older men (66.4 ± 4.6 years) were assigned to control or experimental (Exp) group (n = 13 per group). The(More)
This study compared the effect of four different intensities of initial eccentric exercise (ECC1) on optimum angle shift and extent of muscle damage induced by subsequent maximal eccentric exercise. Fifty-two male students were placed into 100%, 80%, 60%, or 40% groups (n = 13 per group), performing 30 eccentric actions of the elbow flexors of 100%, 80%,(More)