Travis L. Knuckles

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BACKGROUND Emerging evidence suggests that the systemic vasculature may be a target of inhaled pollutants of vehicular origin. We have identified several murine markers of vascular toxicity that appear sensitive to inhalation exposures to combustion emissions. OBJECTIVE We sought to examine the relative impact of various pollutant atmospheres and specific(More)
Epidemiological studies suggest that living near mountaintop coal mining (MTM) activities is one of the contributing factors for high lung cancer incidence. The purpose of this study was to investigate the long-term carcinogenic potential of MTM particulate matter (PMMTM) exposure on human bronchial epithelial cells. Our results show that chronic exposure(More)
In the version of this article originally published, the statement under Materials and Methods " In comparison with PM CON , Si and Mo were found to be the main inorganic chemical elements in PM MTM with the % weight-average of 48.15 ± 26.91% and 28.90 ± 4.16%, respectively, for Si and Mo versus 23.75 ± 15.07% and 0.00 ± 0.00% of the elements in PM CON "(More)
Epidemiological studies have associated air pollution particulate matter (PM) exposure with adverse cardiovascular effects. Identification of causal PM sources is critically needed to support regulatory decisions to protect public health. This research examines the in vitro cardiotoxicity of bioavailable constituents of residual oil fly ash (ROFA) employing(More)
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