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The generation of second messengers from the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdInsP2) by phospho-inositidase C has been implicated in the mediation of cellular responses to a… (More)
Objective: To use PCR based detection of B. burgdorferi to predict treatment response in Lyme neuroborreliosis.
A central challenge for improving autoimmune therapy is preventing inflammatory pathology without inducing generalized immunosuppression. T helper 17 (TH17) cells, characterized by their production… (More)