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Stimulants of protease-activated receptor-2 (PAR(2)), such as Ser-Leu-Ile-Gly-Arg-Leu-NH(2) (SLIGRL), cause airway smooth muscle relaxation via the release of the bronchodilatory prostanoid prostaglandin E(2) (PGE(2)). The principal aim of the current study was to determine whether compounds that inhibit PGE(2) reuptake by the prostaglandin transporter(More)
The effects of Juzen-Taiho-To (JTT), a Kampo (Japanese herbal) medicine, on Peyer's patch cells mediated hematopoietic response were investigated. When the conditioned medium of Peyer's patch cells obtained from C3H/HeJ mice, which had orally administered JTT for 7 consecutive days, was added to the culture medium for bone marrow cells, the cells(More)
Blood collected in ACD was supplemented with PIGP solution or PIGPA solution. The presence of adenine enhanced the mechanical resistance to trauma of erythrocytes. The levels of 2,3-diphosphoglycerate and adenosine triphosphate were restored to a normal to subnormal level. The PIGPA media seemed satisfactory for rejuvenation of stored blood for freezing(More)
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