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Each aminoacyl-tRNA synthetase must functionally distinguish its cognate tRNAs from all others. We have determined the minimum number of changes required to transform a leucine amber suppressor tRNA… Continue Reading
IN the presence of costimulation1, Ca2 + influx in T cells leads to activation (transcription of interleukin-2; ref. 2) via calcineurin3,4. In the absence of costimulation, Ca2+ influx results in… Continue Reading