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We recently reported that circulating apolipoprotein AII (apoAII) isoforms apoAII-ATQ/AT (C-terminal truncations of the apoAII homo-dimer) decline significantly in pancreatic cancer and thus might serve as plasma biomarkers for the early detection of this disease. We report here the development of novel enzyme-linked immunosorbent assays (ELISAs) for(More)
We consider a complete noncompact Riemannian man-ifold M and give conditions on a compact submanifold K ⊂ M so that the outward normal exponential map off of the boundary of K is a diffeomorphism onto M \K. We use this to compactify M and show that pinched negative sectional curvature outside K implies M has a compactification with a well defined Hölder(More)
OBJECTIVE Our objective was to assess whether the occurrence of medically attended local reactions to intramuscularly administered vaccines varies by injection site (arm versus thigh) in children 1 to 6 years of age. METHODS This is a retrospective cohort study of children in the Vaccine Safety Datalink population from 2002 to 2009. Site of injection and(More)
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