Tracey M Mahoney

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Recent evidence from our laboratory demonstrates that platelets synthesize numerous proteins in a signal-dependent fashion (Pabla, R., Weyrich, A. S., Dixon, D. A., Bray, P. F., McIntyre, T. M., Prescott, S. M., and Zimmerman, G. A. (1999) J. Cell Biol. 144, 175-184; Weyrich, A. S., Dixon, D. A., Pabla, R., Elstad, M. R., McIntyre, T. M., Prescott, S. M.,(More)
For most cells the nucleus takes center stage. Not only is it the largest organelle in eukaryotic cells, it carries most of the genome and transcription of DNA to RNA largely takes place in the nucleus. Because transcription is a major step in gene regulation, the absence of a nucleus is limiting from a biosynthetic standpoint. Consequently, the anucleate(More)
Gastroesophageal reflux is a disorder with well-characterized histopathological features in the adult, but the incidence and pathogenesis of epithelial injury in children are poorly understood. Esophageal suction biopsies from 80 infants exhibiting symptoms of reflux were studied by computer-assisted image analysis and the results compared to routine(More)
Chordomas are slow growing malignant neoplasms with a prolonged clincial course which do not usually metastasize. They are histologically benign, locally invasive and often recur following resection. Survival has been shown to vary widely and prognostic indicators have been difficult to identify. Cellularity, mitotic activity and cellular pleomorphism have(More)
OBJECTIVE To develop and evaluate a diagnostic algorithm based on the alteration of mast cell and nerve fiber observed in bladder tissue of patients with interstitial cystitis (IC). MATERIALS AND METHODS Non-IC samples from 6 control groups (N = 10, 10, 13, 2, 11, and 3, respectively) and nonclassic interstitial cystitis (NC-IC, N = 20) were stained with(More)
Apgar scores of 0-4 at 1 minute and 0-6 at 5 minutes have been investigated as risk criteria in the Utah High Risk Hearing Screening Program. The 1990 Joint Committee on Infant Hearing (JCIH) statement recommended only an Apgar score of 0-3 at 5 minutes be included in a risk registry for sensorineural hearing loss (SNHL). An analysis of live births(More)
Twenty-eight surgically confirmed otosclerotic ears were evaluated to determine whether tympanometric admittance measurements could differentiate otosclerosis from a normal population. Subjects were tympanometrically measured at test conditions B220, B660, G220 and G660 Hz. When comparing mean curve peak amplitude to normative standards, 20 ears showed(More)
This study was designed to investigate the premise that the long-term use of monaural amplification influences dichotic listening conditions in a population with sensorineural hearing losses. 30 subjects with moderate, bilateral sensorineural hearing losses and 10 normally-hearing adults were chosen for this study. 20 of the subjects with sensorineural(More)
State-wide, high-risk hearing screening is made possible in Utah through the use of a questionnaire designed for maternal response during hospitalization. The mothers of those determined high risk are sent a follow-up questionnaire when the infant is 6 to 8 months of age, and a determination is made for audiological testing on the basis of her response.(More)
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