Tracey Harding

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Multiple myeloma (MM) is characterized by significant genetic diversity at subclonal levels that have a defining role in the heterogeneity of tumor progression, clinical aggressiveness and drug sensitivity. Although genome profiling studies have demonstrated heterogeneity in subclonal architecture that may ultimately lead to relapse, a gene expression-based(More)
AIMS AND OBJECTIVES To investigate the links between the binge pattern of drinking and the development of cognitive impairment in young adults in the UK. To determine from the findings whether cognitive impairment is an additional public health concern manifesting from this form of alcohol misuse and its relevance to nursing practice. BACKGROUND Young(More)
Extensive interindividual variation in response to chemotherapy is a major stumbling block in achieving desirable efficacy in the treatment of cancers, including multiple myeloma (MM). In this study, our goal was to develop a gene expression signature that predicts response specific to proteasome inhibitor (PI) treatment in MM. Using a well-characterized(More)
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