Toyoko Matsui

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In an attempt to describe the characteristics of febrile convulsions (FC) 133 children with a history of FC were checked neurologically at health centers in northern Japan. Using categorical data from principal component analysis, family history of FC, recurrence and body temperature prior to convulsion, EEG disorders, exogenous factors, age at onset as the(More)
PURPOSE Diagnosis of amyotrophic lateral sclerosis (ALS) at an early stage is challenging, thus making the enrollment of these patients in clinical trials infeasible. In this study, we investigated the potential usability of motor unit number index (MUNIX) to detect denervation of clinically intact muscles of ALS patients. METHODS Thirty-two first dorsal(More)
C-reactive protein (CRP) levels were measured using a new particle-mediated immunoassay. Tests for precision and linearity of this method gave satisfactory results. The minimum sensitivity of the assay was 1 ng/ml. Interference by bilirubin (<220mg/l) and haemoglobin (<20g/l) was not observed. Using this method, CRP was assayed as a means of monitoring for(More)
A 41-year-old woman developed horizontal diplopia and difficulty in moving her eyes. On neurological examination, her eyes showed absolute bilateral horizontal gaze palsy, but convergency and vertical eye movement were normal. The cerebrospinal fluid findings revealed an increased IgG level and myelin basic protein. T2-weighted magnetic resonance imaging(More)
We studied 50 patients with Parkinson's disease to determine any relation of epidemiologic factors (such as the duration of illness), the duration of levodopa therapy, the total amount of administered levodopa to degree of autonomic dysfunction. Autonomic dysfunction was evaluated using the composite autonomic scoring scale (CASS). The CASS scores were(More)
We report a patient who had generalized painful muscle cramps associated with isolated ACTH deficiency. A 68-year-old woman was hospitalized because of painful muscle cramps present for one year. Neurological examination revealed no abnormalities except for generalized painful muscle cramps. Serum electrolyte and CPK levels were normal. Serum ACTH and(More)
Lead acetate exposure to humans can induce various disorders of the cranial nerves. Although vertigo and sensorineural deafness have been reported in lead workers, the dose effects of lead acetate on the cochlea and eighth cranial nerve are not well documented. We investigated the effects of lead acetate on the male albino Hartley guinea pig cochlea by(More)
A 15-year-old girl (case 1) was admitted to our hospital because of progressive muscle weakness of the lower limbs and numbness of the upper limbs. She noted these symptoms beginning at 13 years of age. Neurological examination revealed that deep tendon reflexes were absent and hypesthesia of touch and pain sensation were distributed in a glove-and-stocking(More)
By examining 218 albino guinea pigs, electrophysiological methods were used to investigate the effects of low frequency ultrasound at moderate sound pressure levels after long-term exposure to the inner ear. From 10 kHz to 28 kHz, low frequency ultrasound below 100 dB SPL induced significant changes in cochlear microphonics, elevated thresholds and(More)