Toyanji Joseph

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In the present study, the putative antihyperglycemic and antioxidant effects of a flavanone, naringenin, were evaluated in comparison with those of glyclazide, a standard drug for therapy of diabetes mellitus. Diabetes was induced experimentally in 12-h-fasted rats by intraperitoneal injections of first streptozotocin (50 mg/kg b.w.) and then of(More)
Voltage instability is a major issue that attracts worldwide interest because of its consequence of voltage collapses. These days power systems operate closer to their stability limits, transferring large amounts of powers from long distance and an inadequate supply of reactive power contribute to system voltage instability and eventually lead to voltage(More)
OBJECTIVE To identify novel inhibitors of dopamine beta hydroxylase (DBH) and evaluate their antihypertensive properties in L-NAME induced hypertensive rat model. DESIGN AND METHOD An experimentally validated computational model for hDBH, built in our lab, was used for structure-based, rational drug-design. The three-dimensional model was used for(More)
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