Toshiyuki Tasaki

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BACKGROUND Suplatast tosilate is an anti-allergic agent that suppresses cytokine production by human Th2 cells. OBJECTIVE We investigated the effects of suplatast tosilate on the production of thymus- and activation-regulated chemokine (TARC) by T cells from allergic patients with asthma. METHODS Purified protein derivative (PPD)-specific Th1 cell lines(More)
BACKGROUND Nebulized lidocaine enables dosages of oral corticosteroids to be tapered in the treatment of severe asthma. OBJECTIVE We sought to investigate the effect of lidocaine on T cells from patients with allergic asthma. METHODS PBMCs and CD4(+) T cells were isolated from 6 patients with asthma and house dust mite allergy. PBMCs were cultured with(More)
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