Toshiro Mori

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Changes in peak time and amplitude of the direct current registered c-wave of the electroretinogram of the albino rabbit were investigated with various stimuli of duration ranging from 0.25 to 10 sec. The stimulus intensity was 500 lux at the surface of the cornea. Slow PIII was isolated by administrations of sodium iodate and sodium aspartate. The peak(More)
In an attempt to simplify the recording technique in electrophysiologic evaluation of the retinal pigment epithelium, we combined the electro-oculographic light rise, hyperosmolarity and acetazolamide responses in a single recording session. Recordings were performed in six normal subjects and in seven patients with diabetic retinopathy or retinitis(More)
The toxicity of β-blocker, Befunolol HCl (BFE), to the retinal pigment epithelium was investigated electrophysiologically. Rabbit in vivo ERG b- and c-waves were recorded after intravitreal injections of 0.1 ml of 0.25, 1, 2, 4, 6 and 10% BFE solutions with osmolalities of 304, 340, 383, 432, 493 and 618 mOsm repsectively. Phosphate solutions with osmotic(More)
TEI-2117 (I), 2-(3-benzoyl-2, 5-dimethylpyrrole) propanol, is a novel compound synthesized by our laboratories. The effect of I was studied on human platelet aggregation and on prostaglandin biosynthesis in vitro comparing with indomethacin (IM). The compound (I) was more potent inhibitor than IM in arachidonic acid-induced platelet aggregation. I had(More)
Three cases of congenital stationary night blindness are reported. In all patients a negative electroretinogram was recorded by single bright flash stimulation and changed to positive on sequential reduction of the stimulus intensities. Oscillatory potentials were recognized. Biphasic dark adaptation curves and moderate elevation of the relative logarithmic(More)
Increased choroidal pressure and choroidal stasis were induced in Dutch rabbit eyes by tying off vortex veins. Ligating one to three vortex veins caused a progressive diminution in the b- and c-waves of the electroretinogram so that the amplitudes were approximately half of control values when three vortices had been ligated. After ligation of four vortex(More)
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